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Anti-ER/ESR1 Antibody (Clone#OTI1B1)

Mouse monoclonal antibody

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筛选器: All IHC WB

MA00057

  • 50μl ¥1280 100μl ¥2180 150μl ¥2800
  • 货期: 5-7天
  • Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Figure from citation: Western Blot of ESR1 protein level by using anti-ESR1 antibody in human breast cancer tissues (T) and normal tissues (N). View Citation

    all(10)
  • Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ESR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, MA00057)

    all(10)
  • HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ESR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ESR1(Cat# MA00057).

    all(10)

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产品简介>

产品名称
Anti-ER/ESR1 Antibody (Clone#OTI1B1)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
ER; ER alpha; Era; ERα; ESR; ESR1; ESRA; Estradiol receptor; Estrogen receptor; estrogen receptor 1; NR3A1
产品类型
Monoclonal
检验物种
human, mouse, rat
应用范围
IHC, WB
基因名称
ESR1
克隆号
OTI1B1
宿主
Mouse
抗体亚型
IgG2b
免疫原
Full length human recombinant protein of human ESR1(NP_000116) produced in HEK293T cell.
计算分子量
66 kDa
实际分子量
66 kDa
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度
500 ug/ml
产品形态
Liquid
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
Estrogen receptor alpha (ER-α), also known as NR3A1, is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen. Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. In humans, ER-α is encoded by the gene ESR1 (Estrogen Receptor 1). It is mapped to 6q25.1. This gene is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, it also play a role in other tissues such as bone.
Uniprot ID
P03372  
文献引用格式
ER/ESR1 Antibody (Clone#OTI1B1) (Boster Biological Technology, Wuhan, China. Catalog#MA00057)
应用释义
WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC-免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法
基因名全称
estrogen receptor 1
蛋白名全称
Estrogen receptor
推荐稀释比
Western blot (WB):1:2000
Immunohistochemistry (IHC):1:150

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    Anti-ER/ESR1 Antibody (Clone#OTI1B1)

    筛选器: All IHC WB

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