产品名称
Anti-CA15-3/MUC1 Antibody (Clone#GP1.4)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
CA15 3; CA153; CA15-3; Carcinoma associated mucin; CD227; EMA; Episialin; H23AG; KL-6; MAM6; MUC 1; MUC1; MUC1 beta; MUC1 CT; MUC1 NT; MUC1/CA15-3 C-terminal; Mucin 1; Peanut reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor associated mucin
免疫原
Human milk fat globule membranes.
成分
200ug/ml antibody with PBS ，0.02% NaN3 , 1mg BSA and 50% glycerol.
保存条件
12 months from date of receipt，-20℃ as supplied.
背景资料
MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1(EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type I transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
文献引用格式
CA15-3/MUC1 Antibody (Clone#GP1.4) (Boster Biological Technology, Wuhan, China. Catalog#BM0042)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
推荐配套的二抗和检测试剂
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.
基因名全称
mucin 1, cell surface associated
推荐稀释比
| Immunohistochemistry (IHC): | 1:50-400 |
| (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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